Gun Laws Essay Example | Topics and Well Written Essays - 500 words

Enzymes Essay example -- essays research papers

The structure of the chemical is for the most part reliant on the dynamic site and variable gatherings. Extraordinary temperatures or outrageous pHs can adjust the structure of a compound. Proteins capacity to bring down the initiation vitality to break the bonds. They accomplish this by squeezing the securities or making a microenvironment for the substrate. Chemicals are controlled by inhibitors or on the other hand activators and can be repressed by the results of the response, called criticism hindrance. Catalysts are synergist proteins; in this way they change the pace of a response without being expended. This implies once and compound carries out its responsibility it can in any case play out a similar capacity as it did previously. Natural impetuses change the pace of a response without being for all time changed. Proteins are polypeptides that are comprised of amino acids. Protein variable gatherings that are uncovered are the spots where natural procedures happen. These side chains, usually called "R groups," make up the dynamic site and catalyze the change of the substrate to make an item. These side chains are regularly called variable bunches since they are frequently what decides the sort of catalyst it is, in this manner figuring out what substrates it will security with. An adjustment in temperature or a vacillation in pH can change the enzyme’s structure. Anent temperature the modification of the proteins happens when the temperature is extremely high and the compound denatures and can't play out the ideal errand. The temperature is high to such an extent that the dynamic site of the protein changes and it can't security with substrates. The pH at which various compounds denature contrasts from catalyst to chemical. Like too high a temperature, if a particular catalyst is at a pH at which the dynamic site changes, the compound can't work. This delineates how the structure of a catalyst is indispensable to its legitimate working. Allosteric chemicals vary in structure than the past catalysts tended to. The extraordinary temperature and pH rules, notwithstanding, still apply. Most allosteric compounds are made out of at least two sub units, each having its own dynamic site. The allosteric proteins are continually changing between two conformational states, dynamic and dormant states anent working. This wavering aides in the guideline of the proteins. Chemicals work as natural impetuses, implying that they are natural particles (proteins) that change ... ...r to the allosteric site while the compound is in the idle structure will hinder the capacity of the compound to work. Cooperativity is the point at which a substrate ties to the dynamic site of an allosteric catalyst in this manner leaving the compound in dynamic structure and supporting in the official of different proteins to the next dynamic locales of the compounds. Criticism hindrance happens when a metabolic pathway is killed by the finished result of the response. For instance, the final result of a particular response may be an allosteric inhibitor to the particular compound that makes the item; this forestalls the protein to make more items when they are not required. As the item gathers the item hinders the blend or items. All in all, the structure of the protein is fundamentally subject to the dynamic site and variable gatherings. Outrageous temperatures or extraordinary pHs can change the structure of a protein. Compounds capacity to bring down the actuation vitality to break the bonds. They accomplish this by putting pressure and pressure on the securities or making a microenvironment for the substrate. Proteins are managed by inhibitors or activators and can be hindered by the results of the response, called input restraint. Catalysts Essay model - papers inquire about papers The structure of the catalyst is essentially subject to the dynamic site and variable gatherings. Extraordinary temperatures or outrageous pHs can adjust the structure of a protein. Compounds capacity to bring down the actuation vitality to break the bonds. They accomplish this by squeezing the securities or making a microenvironment for the substrate. Proteins are directed by inhibitors or on the other hand activators and can be restrained by the results of the response, called input hindrance. Chemicals are synergist proteins; along these lines they change the pace of a response without being devoured. This implies once and chemical carries out its responsibility it can even now play out a similar capacity as it did previously. Natural impetuses change the pace of a response without being for all time changed. Compounds are polypeptides that are comprised of amino acids. Chemical variable gatherings that are uncovered are the spots where organic procedures happen. These side chains, usually called "R groups," make up the dynamic site and catalyze the transformation of the substrate to make an item. These side chains are frequently called variable bunches since they are regularly what decides the sort of compound it is, hence figuring out what substrates it will security with. An adjustment in temperature or a vacillation in pH can modify the enzyme’s structure. Anent temperature the change of the chemicals happens when the temperature is extremely high and the catalyst denatures and can't play out the ideal assignment. The temperature is high to such an extent that the dynamic site of the chemical changes and it can't security with substrates. The pH at which various proteins denature varies from compound to catalyst. Like too high a temperature, if a particular chemical is at a pH at which the dynamic site changes, the chemical can't work. This delineates how the structure of a catalyst is crucial to its appropriate working. Allosteric chemicals contrast in structure than the past compounds tended to. The extraordinary temperature and pH rules, in any case, despite everything apply. Most allosteric catalysts are made out of at least two sub units, each having its own dynamic site. The allosteric proteins are continually changing between two conformational states, dynamic and latent states anent working. This swaying helps in the guideline of the catalysts. Chemicals work as natural impetuses, implying that they are natural particles (proteins) that change ... ...r to the allosteric site while the catalyst is in the latent structure will block the capacity of the catalyst to work. Cooperativity is the point at which a substrate ties to the dynamic site of an allosteric compound hence leaving the catalyst in dynamic structure and supporting in the authoritative of different proteins to the next dynamic destinations of the catalysts. Input restraint happens when a metabolic pathway is killed by the final result of the response. For instance, the finished result of a particular response may be an allosteric inhibitor to the particular catalyst that makes the item; this forestalls the protein to make more items when they are not required. As the item collects the item hinders the combination or items. Taking everything into account, the structure of the chemical is for the most part subject to the dynamic site and variable gatherings. Extraordinary temperatures or outrageous pHs can adjust the structure of a chemical. Compounds capacity to bring down the initiation vitality to break the bonds. They accomplish this by putting pressure and pressure on the securities or making a microenvironment for the substrate. Catalysts are directed by inhibitors or activators and can be restrained by the results of the response, called criticism restraint.

Is It Safer to Be a Pessimist

Is It Safer to Be a Pessimist Theories Personality Psychology Print Is It Safer to Be Pessimistic? Is Optimism Really More Beneficial? By Elizabeth Scott, MS twitter Elizabeth Scott, MS, is a wellness coach specializing in stress management and quality of life, and the author of 8 Keys to Stress Management. Learn about our editorial policy Elizabeth Scott, MS Updated on May 29, 2019 Image Source/Getty Images More in Theories Personality Psychology Myers-Briggs Type Indicator Behavioral Psychology Cognitive Psychology Developmental Psychology Social Psychology Biological Psychology Psychosocial Psychology Pessimists sometimes are better prepared for tough times. If you’re a pessimist, you may foresee obstacles more readily, expect things to go wrong, and perhaps plan for difficulties more readily. Pessimists are more likely to build safety nets, and pessimists don’t find their world views coming into question when things go wrong; they already expect that to happen! So why don’t I recommend that people become pessimists? Benefits of Optimism Scientific research in the field of Positive Psychology tells us that optimists gain so many benefits from their world view that it may be worth the added disappointment they may face in setbacks: optimists tend to be healthier, happier, more successful (financially, socially, and in many other ways), and enjoy stronger and more satisfying relationships. If this sounds like optimists fare better in virtually every area of life, that’s because it’s true. (Read more about the benefits of optimism.) The Difference Between Optimists and Pessimists Right now, optimism is sounding pretty great, and it is. But before I go on, I want to explain the difference between an optimist and a pessimist: it all has to do with explanatory style  or the way people interpret what happens in their lives. An optimist will take positive events and magnify them, while minimizing the negative in a situation; a pessimist will do the opposite and downplay the positive while really focusing on the negative. (There’s a specific way in which this happens; read more about it in the article about traits of optimists.) This is important because the tendency to minimize the negativeâ€"one of the traits that encourages optimists to dream big and emboldens them to keep on trying even after they face setbacksâ€"can also produce a false sense of security that may cause optimists to fail to conceive of possible difficulties and plan for them. It may also lead them to feel surprised when things don’t go their way. However, these very traitsâ€"minimizing the negative and maximizing the positiveâ€"can help an optimist through tough times that could send a pessimist to a darker, more helpless place. Even when things seem to be falling apart, an optimist will seek new solutions instead of dwelling on problems; they’ll have hope to get through hard times, and trust that they’ll come out the other side soon enough; they’ll have the wherewithal to turn a negative situation into a positive one. Therefore, pessimists may be less surprised when crises occur, but optimists don’t stay in negative situations for as long; they find a way to dig themselves out. Stay Optimistic While Still Being Prepared So how can you stay optimistic without missing opportunities to keep yourself prepared for crises? Here’s what I recommend: Hope for the best, and plan for the worst. This allows you to have many benefits of optimism without leaving yourself vulnerable and unprepared. Like a pessimist think about things that can possibly go wrong, and try to find back-up plans and contingencies for dealing with the unexpected. (This can help you to feel more prepared if things take a turn in a less desirable direction, and can help you remember that different paths can still work.)Remember what’s important.Savor what you have, and also remind yourself that you are more than what you have; you have strength independent of things in your life that give you power. You may want to take time, periodically, to take inventory of your own strengths and resources. Stress results when we feel the demands of a situation exceed our resources to handle them; keeping in mind what your resources are can reduce stress and help you feel empowered as you move through life. This can really help when you’re facing a crisis.Cultivate grat itude.Be grateful for what you have, without becoming so attached to it that you can’t imagine your life without it. This is a tricky one, and takes practice, but ultimately can be done and is a worthy goal. The practices of mindfulness and meditation have been helpful for many in this regard.Expect the unexpected. If things don’t go according to plan, it doesn’t mean that this is the end of the story. There are gifts in every situation, even those that we don’t expect.Remember that whatever you face will pass. One thing that Positive Psychology research has taught us is that major setbacks do not cause people to feel unhappy for as long as people predict. After a few weeks or, in some cases, months, people who have experienced a major crisis generally return to their regular level of happiness (or unhappiness). Optimists tend to feel happier in general, and pessimists tend to feel less happy than that, but if you’re a pessimist, it’s always possible to be a ‘learned o ptimist’. Sometimes enduring a crisis provides you with just the right motivation to do that. (Read this article for more on how to become an optimist.)Value what you have, in any situation. Even if you’ve lost a lot, there are still things that you have to cherish. Studies show that, other than those in poverty, people with a lot of money generally aren’t happier than people with a little; lottery winners, even, aren’t significantly happier than those who have lost the use of their legs, once a few months have passed. But those who have close friends, those who feel gratitude, and those who have a sense of meaning in life the happiest. Focus on what you still have, and you’ll feel like you have some really good things in your life.

Make an Inference Practice Questions

Want to master your reading comprehension? Practicing your inference skills is a great place to start, but if you are unsure how to make an inference at all (or what one even is), you might want to start with the  basics of inference  which will give you all of the  details that you need. If you are ready to go, go ahead and get started with these easy inference practice questions to hone your reading skills. The following inference questions provide a basic assessment of your comprehension of the skill. Printable PDFs: Inference Practice Questions 1 | Answers to Inference Practice Questions 1 Inference Practice Questions 1 Using your best inference strategies, make an inference about the following statements. The first two are done for you. I wouldnt eat after that two-year-old if I were you.Inference: The two-year-old probably did something gross to the food you were about to eat or has a cold and you could catch it. Something bad will happen to you if you eat  the food.  For Valentine’s Day, my fantastic neighbor gave his wife a poem that took him about two seconds to write. Sheesh.Inference: My neighbor is not very considerate since he didnt take his time writing the poem.A man ran after a retreating bus, waving his briefcase frantically.Inference:If she died, I wouldn’t go to her funeral.Inference:Jake almost wished that he hadn’t listened to the radio. He went to the closet and grabbed his umbrella even though he would feel silly carrying it to the bus stop on such a sunny morning.Inference:Hey! What happened to all the school construction money taken from the taxpayers? It paid for this toilet the money was flushed down.Inference:As you give a speech in front of a large audience, you reali ze that people are laughing behind their hands and pointing to the region below your waist.Inference:No, Honey, I don’t want you to spend a lot of money on my birthday present. Just having you for a husband is the only gift I need. In fact, I’ll just drive my old rusty bucket of bolts down to the mall and buy myself a little present. And if the poor old car doesnt break down, I’ll be back soon.Inference:A woman walks into a hospital clutching her abdomen and yelling at  her husband, who trails behind her carrying a large bag.Inference:Youre driving on the highway, listening to the radio, and a police officer pulls you over.Inference: Inference Practice 1 Suggested Answers 3. A man ran after a retreating bus, waving his briefcase frantically. Inference:  The man had to take that bus to work and he was running late. He wanted the bus driver to stop the bus so he could get on it. 4. If she died, I wouldn’t go to her funeral. Inference:  Im extremely angry with this woman for some major  reason,  because one of the worst things a person could do is to hate someone after they have passed away. 5. Jake almost wished that he hadn’t listened to the radio. He went to the closet and grabbed his umbrella even though he would feel silly carrying it to the bus stop on such a sunny morning. Inference:  Jake heard that it was going to rain later in the day. 6. Hey! What happened to all the school construction money taken from the taxpayers? It paid for this toilet the money was flushed down. Inference:  The school district is wasting tax payers money. 7. As you give a speech in front of a large audience, you realize that people are laughing behind their hands and pointing to the region below your waist. Inference:  You forgot to zip up your fly or you have something on your pants. 8. No, Honey, I don’t want you to spend a lot of money on my birthday present. Just having you for a husband is the only gift I need. In fact, I’ll just drive my old rusty bucket of bolts down to the mall and buy myself a little present. And if the poor old car doesnt break down, I’ll be back soon. Inference:  The wife wants the husband to buy her a new car for her birthday. 9. A woman walks into a hospital clutching her abdomen and cursing out her husband, who trails behind her carrying a large bag. Inference:  The woman is in labor. 10. Youre driving on the highway, listening to the radio, and a police officer pulls you over. Inference:  Youve broken the law in some way while driving.

The Cognitive Behavior Theory, Anger, And Anger - 1253 Words

Anger is a strong emotion of displeasure caused by some type of grievance that is either real or perceived to be real by a person. The cognitive behavior theory attributes anger to several factors such as past experiences, behavior learned from others, genetic predispositions, and a lack of problem-solving ability. To put it more simply, anger is caused by a combination of two factors: an irrational perception of reality (It has to be done my way) and a low frustration point (It s my way or no way). Anger is an internal reaction that is perceived to have a external cause. Angry people almost always blame their reactions on some person or some event, but rarely do they realize that the reason they are angry is because of their irrational perception of the world. Angry people have a certain perception and expectation of the world that they live in and when that reality does not meet their expectation of it, then they become angry. It is important to understand that not all anger is unhealthy. Anger is one of our most primitive defense mechanisms that protects and motivates us from being dominated or manipulated by others. It gives us the added strength, courage, and motivation needed to combat injustice done against us or to others that we love. However, if anger is left uncontrolled and free to take over the mind and body at any time, then anger becomes destructive. Why We Need to Control Anger Just like a person who is under the control of a street drug---a personShow MoreRelatedThe Anger Management Program For A Group Therapy Workshop Setting Essay1591 Words   |  7 Pagescounseling services, anger management is offered in a group therapy workshop setting. The clients attending are multicultural females ranging in age from mid-twenties to sixties (males have a separate group). 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Owl City-Ocean Eyes by Owl City free essay sample

Everybody’s heard of the recent hit song â€Å"Fireflies†. The song is by Owl City, which is mainly composed of artist Adam Young and his computer. Plagued with insomnia, he passed the time by playing with his parents’ computer and uploaded his first song to MySpace-â€Å"Hello Seattle†. Owl city, in my opinion, is a very refreshing change from the songs out there about love and sex. Almost all the songs out there have something to do with love. What has this world gotten to-a world of people crazed by romantic fantasies? I love how most of his songs doesn’t even mention a word related to romance. His songs display his quirky and eccentric personality. He even writes about going to the dentist. I mean, who is creative enough to write about something that ordinary and making it worth listening to? With a soothing, almost hypnotic voice, backed up with interesting techno-style backup music, Adam works his way through seemingly random lyrics and into your heart. We will write a custom essay sample on Owl City-Ocean Eyes by Owl City or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page His songs are different every time, and all of them have little hidden meanings that you have to really look for. His most recent album, Ocean Eyes, is based around metaphoric and symbolic ideas, like nature, and his lyrics really show more than tell. Lyrics like â€Å"Swallow a drop of gravel and blacktop/cause the road tastes like wintergreen† or â€Å"Every mushroom cloud has its silver lining/though I’m undermining to deep to know† are what makes his songs unique and idiosyncratic. He has also released two other albums-Of June and Maybe I’m Dreaming. It’s difficult not to be pulled into his music as his voice flies smoothly over you. I like to listen to his music when I run, or when I do homework, and before I go to bed. It does wonders on lifting your mood. How long does it take for you to get bored of hearing about a bad romance? Owl City is something you can listen to over and over again, and never get bored of. So if you loved â€Å"Firef lies†, or like techno music, or is just plain sick of the endless love stories being recycled over and over again in popular songs, check out Owl City!

Mastering Semantic Technology for Success with Ontotext Live Online Trainings

Mastering Semantic Technology for Success with Ontotext Live Online Trainings How It All Started Everything should be made as simple as possible, but not simpler.Albert EinsteinDecember 2016. This is when the first live online training in Semantic Technology organized by a bunch of enthusiasts at Ontotext took place. It was certainly not the first training on the subject in the world. But it was an important step in our efforts to proactively communicate the advantages of Semantic Technology.Ever since Ontotext started piling up knowledge in the field, we have been sharing our expertise through trainings. However, these have always been created as a result of specific requests from clients.But in the winter of 2016, we decided to change that. Instead of waiting for people to approach us, we wanted to be at the forefront of educating them about how certain semantic tools could help them solve various data analytics challenges. Here’s our story. A Closer Look at Who We AreFor more than 20 years, Ontotext has been in the business of developing and providing Semantic Technology-based solutions for various domains. As a result, we’ve accumulated (often after some trial-and-error) a lot of valuable experience. This has helped us understand which solutions would work best depending on specific domains and use cases.It has also made us aware of the major pain points that people could come across when adopting Semantic Technology solutions. So, it was almost a matter-of-course that the idea of organizing all this knowledge into a coherent and easy-to-grasp learning journey was born. The Challenge of Designing Have-it-all TrainingsThere are three things to remember when teaching: know your stuff, know whom you are stuffing, and then stuff them elegantly.Lola J. May, Mathematics EducatorOnce you know your destination, you just need to start walking, right? Wrong. Before we could share our experience, first we needed to clearly define the audience that would benefit from such broader training courses. To do that, we had to decide which Semantic Technology adoption pain points we wanted to focus on to best meet people’s needs.Equally important, we needed to determine the format and the kind of content coverage that would be most useful for it. We didn’t just want to go in front of people and talk about what we knew and found interesting. We wanted to shape our expertise to fit what people actually needed to know. And do it in a way that made it easy and intuitive for them to apply when dealing with their own use cases.The Matter at HandAfter some consi deration, we decided that we wanted to focus on two areas where we thought our impact on people’s needs would be most significant.The first was to improve people’s understanding of the importance and the practical advantages of using Semantic Technology when solving various knowledge management and data analytics problems. This is how our Designing a SemTech PoC training was born.The second was to provide the best (and quickest) way for people to delve in and start working with our leading semantic graph database, GraphDB. This is how our GraphDB for DevOps training came about.Ways and MeansOnce the scope of the new training courses was defined, we looked at the pros and cons of different formats.Based on our experience from the tailored trainings, we decided that the best setup for sharing our practical experience and nurturing a community of like-minded Semantic Technology enthusiasts was to offer a live online format to a small group of participants. In this way, we could have more space for interchange and we could keep a close eye on people’s progress.We also anticipated that if our guidance proved beneficial for people, we could establish a schedule of recurring trainings. As an additional benefit, having recurring courses would also allow us to check if we were on the right track.Shaping Our OfferTo teach is to learn twice over.Joseph JoubertWhen we designed the original curriculum for our training courses, we had a pretty good idea of what we wanted to demonstrate the content coverage, the exercises, the individual assignments, etc.However, each iteration of a training was a chance to change and, hopefully, improve important details from content to delivery. This was mostly thanks to people’s feedback, but also the selected format allowed us to see what worked best and what didn’t.The most important lesson we have learned is that a training is always a work in progress. Each following edition has the potential to be better than the previous one both in terms of what we teach and how we teach it.Eight Editions of Designing a SemTech PoC LaterOur Designing a SemTech PoC training has evolved significantly from the first basic demonstration of what we considered to be the most important techniques. In the beginning, our live sessions focused on cramming as much useful information as possible about data integration (through OntoRefine) and data exploration (with SPARQL). We presented a sample workflow that illustrated how existing resources could benefit from Linked Open Datasets and how to best analyze the available data. As a successful PoC is, in our view, the result of efficient data analytics, we wanted to let the trainees get the feel of such a workflow with the help of some hands-on experience.However, we found that many people struggled with SPARQL. So, with the help of the participants’ feedback, we went through several iterations of redesigning the way we introduced it. We focused on the value of good technical skills in the process of solving an interesting problem. We also introduced a variety of means for data analysis. But most importantly, we decided to simplify the live session as much as possible to make it less difficult for trainees to follow what was c overed and give them more chances to interact.We reworked our use cases and interwove everything we demonstrated into a single story to engage our participants. This made all components of building a PoC easier to understand and refer to at a later stage.We also exported all non-interactive content to the off-line set of additional materials so that participants could study them at their own pace. Instead, we engaged everybody with quick quizzes and discussions on the covered topics.Now, we have a smooth workflow involving a real PoC design that covers all the necessary steps and demonstrates best practices. Shifting our focus to best practices around a single use case story and providing more space for exchange resulted in more lively and productive sessions and happier students.First Steps in GraphDB Training for DevOpsThe GraphDB Training for DevOps is a new course we have designed and started offering this year. It targets developers and operations specialists who interact with GraphDB on a daily basis and need a more in-depth understanding of our semantic graph database. So far, we’ve had only one internal and one public edition of this course, so it’s too early to talk about its progression. But already the internal training has contributed significantly to the improvement of the initial materials.The Bigger PictureA teacher is one who makes himself progressively unnecessary.Thomas CarruthersA year and a half later, Ontotext has offered a total of 14 training courses. This includes our two recurring courses: Designing Semantic Technologies PoC and GraphDB for DevOps. It also includes some custom courses for clients such as Semantic Technologies GATE; Linked Data Sources, Robust Text Analysis and Semantic Search; Gold Standard Corpora; etc.We’ve also collaborated with some universities. We’ve provided materials for the courses Knowledge Modelling and Representation and Knowledge Bases for FMI, University of Sofia. We’ve participated in the preparation of the course Knowledge Representation and Reasoning for the Uni versity of Aberdeen and we have contributed to ESSLLI 2018.Our training courses have had participants from many geographical locations. The use cases of the participants who came to improve their understanding of Semantic Technology in order to further their projects have also been quite diverse. Some were developing flexible data models for representing unstructured or semi-structured data from various domains. Others were working in the area of predictive analytics, or were trying to match and structure information across various sources, or were focused on cancer research.Or, as in the case of Culture Creates, the aim was to make cultural events in Canada findable for voice-powered and AI-powered search assistants. This is possible thanks to metadata enrichment, integrating and linking data from various data sources and, ultimately, dumping, structuring and querying that data with Ontotext’s GraphDB.All Roads Lead to the ClassroomAll in all, our experience has shown that by sharing our expertise in Semantic Technology, we can make a difference. Accommodating all types of busy schedules and non-work related commitments, our training courses allow you to join us from any location.The only disadvantage is that you don’t get to have any of our fragrant coffee and delicious cakes while you follow our demos on your screen at home, but, hey, maybe that’s not such a bad deal either?Interested? Go to our training page where you can learn details  or contact the team for specific questions.